Dalteparin
Dalteparin is a low-molecular-weight heparin (LMWH) that acts as an anticoagulant. It helps prevent the formation of harmful blood clots by enhancing the inhibition of coagulation factors Xa and IIa by antithrombin. It is administered via subcutaneous injection and has a more predictable pharmacological profile compared to unfractionated heparin.
Dosage by Body Weight
Dosage must be individualized based on patient weight, indication, and renal function. Typically administered subcutaneously once or twice daily. Anti-Xa level monitoring may be required in pediatric patients, pregnant women, or those with severe renal impairment.
- Body Weight
- Below 5 kg
- Dose
- 100 - 150 IU per kg
- Frequency
- Every 12 to 24 hours
- Tracking Notes
- Highly specialized pediatric dosing. Use only under strict specialist supervision with anti-Xa monitoring.
- Body Weight
- 5-7 kg
- Dose
- 100 - 150 IU per kg (approx. 500 - 1050 IU)
- Frequency
- Every 12 to 24 hours
- Tracking Notes
- Administer subcutaneously. Monitor anti-Xa levels regularly.
- Body Weight
- 8-10 kg
- Dose
- 100 - 150 IU per kg (approx. 800 - 1500 IU)
- Frequency
- Every 12 to 24 hours
- Tracking Notes
- Dose must be adjusted based on clinical response and lab results.
- Body Weight
- 11-15 kg
- Dose
- 100 - 150 IU per kg (approx. 1100 - 2250 IU)
- Frequency
- Every 12 to 24 hours
- Tracking Notes
- Rotate injection sites to avoid bruising or hematomas.
- Body Weight
- 16-20 kg
- Dose
- 100 - 150 IU per kg (approx. 1600 - 3000 IU)
- Frequency
- Every 12 to 24 hours
- Tracking Notes
- Dosage varies depending on whether prophylaxis or treatment of thrombosis is targeted.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 100 - 150 IU per kg | Every 12 to 24 hours | Highly specialized pediatric dosing. Use only under strict specialist supervision with anti-Xa monitoring. |
| 5-7 kg | 100 - 150 IU per kg (approx. 500 - 1050 IU) | Every 12 to 24 hours | Administer subcutaneously. Monitor anti-Xa levels regularly. |
| 8-10 kg | 100 - 150 IU per kg (approx. 800 - 1500 IU) | Every 12 to 24 hours | Dose must be adjusted based on clinical response and lab results. |
| 11-15 kg | 100 - 150 IU per kg (approx. 1100 - 2250 IU) | Every 12 to 24 hours | Rotate injection sites to avoid bruising or hematomas. |
| 16-20 kg | 100 - 150 IU per kg (approx. 1600 - 3000 IU) | Every 12 to 24 hours | Dosage varies depending on whether prophylaxis or treatment of thrombosis is targeted. |
Formulation
Purpose
Used to prevent and treat blood clots (deep vein thrombosis and pulmonary embolism), reduce the risk of recurring clots in cancer patients, and manage unstable angina or non-Q-wave myocardial infarction.
Generic Name
Dalteparin SodiumBranded Drug Names
Dalteparin is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.